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KMID : 0380420120360030109
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Journal of Prventive Veterinary Medicine
2012 Volume.36 No. 3 p.109 ~ p.113
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Pathological study of Korean native pregnant cows and fetuses experimentally vaccinated with Brucella abortus RB51 in heifers and challenged with Brucella abortus 2308 in pregnancy
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Bae You-Chan
Woo Gye-Hyeong
Kim Ha-Young
Her Moon
Cho Dong-hee
Jung Suk-Chan
Oem Jae-Ku
Byun Jae-Won
Joo Yi-Seok
Lee O-Soo
Lee Myoung-Heon
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Abstract
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Bovine brucellosis causes abortion and infertility. The authors conducted this study in order to determine pathological lesions of Korean native cows and fetuses who received experimental vaccination with Brucella abortus RB51 and were challenged with Brucella abortus 2308. Gross and histopathological lesions in endometrium and placenta were observed in cows of the vaccinated group. Twenty-five percent of pregnant cattle in the vaccinated group showed endometritis and placentitis, which was three times lower, compared with the non-vaccinated group. The pathological lesions in the uterus and placenta in both groups were consistent with previous reports. Therefore, vaccination in heifers using Brucella abortus RB51 may not provide adequate protection against infection with Brucella abortus virulent strain.
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KEYWORD
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Brucella abortus RB51, Cattle, Pathological Lesion
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